Structured nucleic acid nanoparticle therapeutic delivery platform
Project team Mark Bathe, Darrell Irvine, Feng Zhang with Remi Veneziano, Tyson Shepherd and Matthew Stone
Targeted delivery of therapeutics
Targeted, efficient delivery of nucleic acid therapeutics is one of the largest current bottlenecks to the treatment of human diseases. This project will translate structured nucleic acid nanoparticles to the clinic by offering full synthetic control over the chemical composition of the delivery vehicle, homogeneous and reproducible composition, and variable vector conjugation for targeting therapeutic nucleic acid and small molecule payloads to diverse cells and tissues.