Rapid, target-directed antimalarial drug discovery
Project team Jacquin C. Niles with Mai Nakashima, Khan T. Osman, and Charisse F. Pasaje
A global health problem
Malaria remains a major global human health problem. With no efficacious vaccine available, the disease is treated using antimalarial drugs to which resistance is emerging and spreading. This project focuses on establishing a novel strategy for prioritizing antimalarial targets and accelerating discovery of small molecules that interfere with these targeted functions. The goal is the discovery of novel targets and lead compounds for future antimalarial drug development efforts.