Multiplexed measurement of miRNA in tissue sections

Year 2019
Project team Patrick Doyle with Frank Slack, Maxwell Nagarajan and Dana Al-Sulaiman

A key component of medical studies

Spatially resolved gene expression patterns are emerging as a key component of medical studies, including companion diagnostics, yet technologies for quantification and multiplexing are limited. This project is developing a method to perform spatially-resolved and multiplex microRNA measurements directly from formalin-fixed, paraffin-embedded tissue. This technology could be used to quantify the heterogeneities in tissue samples and lead to informed biomarker-based diagnostics.

Spatially Resolved and Multiplexed MicroRNA Quantification from Tissue Using Nanoliter Well Arrays

Published in Nature’s Microsystems & Nanoengineering journal

Dana Al-Sulaiman presents Multiplexed Measurement of miRNA in Tissue Sections at IdeaStream 2021.
Maxwell Nagarajan presents at IdeaStream 2020.