Engineered binding proteins as replacements for antibodies in immunoassays
Project team Hadley Sikes with Eric Miller & Ki Joo Sung
Improving diagnostic tests
Protein biomarkers can be used to indicate illness and injury in humans and in organisms that are consumed as food. Assay development is limited by the availability of high-quality binding molecules, typically antibodies, with appropriate specificity for their target. This project plans to replace antibodies in diagnostic tests with engineered binders for faster development timelines and improved performance.