Development of Synthetic Substrates for Neurodegenerative Disease Platforms

Linda Griffith, Paula Hammond with Marianna Sofman

As the prevalence of neurodegenerative diseases continues to grow, there has been increased attention towards advancing stem cell therapies. This project focuses on developing a synthetic polymer material upon which neural progenitor cells can grow, expand, and differentiate into different neural lineages. This material will yield more homogenous stem cell populations, is advantageous over current poorly defined animal-derived substrates, and will enhance cell attachment that will enable long-term studies.  

See Marianna present their project at IdeaStream 2019 below.

See Marianna present their project at IdeaStream 2018 below.