Rapid, target-directed antimalarial drug discovery

Jacquin C. Niles with Mai Nakashima, Khan T. Osman & Charisse F. Pasaje

Malaria remains a major global human health problem. With no efficacious vaccine available, the disease is treated using antimalarial drugs to which resistance is emerging and spreading. This project focuses on establishing a novel strategy for prioritizing antimalarial targets and accelerating discovery of small molecules that interfere with these targeted functions. The goal is the discovery of novel targets and lead compounds for future antimalarial drug development efforts.

See Charisse Flerida Pasaje present their project at IdeaStream 2020.