Artificial axons as a myelination assay for drug screening in neurological diseases

Krystyn Van Vliet & Nicholas Fang with Anna Jagielska, Daniela Espinosa-Hoyos, Huifeng Du & Seok Kim

Finding cures for neurological diseases is challenging. Most drug candidates fail in clinical trials, in part due to the lack of adequate in vitro drug screening platforms that credibly represent the neural tissue environment. We are developing Artificial Axons, a novel drug-screening platform that mimics biological and mechanical properties of neuronal axons. By providing a better representation of neural tissue, this platform will allow for more predictive in vitro drug development, accelerating finding cures for neurological diseases.

See Anna Jagielska present their project at IdeaStream 2020 below.